On July 21, 2025, the Cleveland Guardians defeated the Baltimore Orioles 10-5 at Progressive Field, improving their record to 49-50 and holding second place in the AL Central. The Orioles, now 44-55,

José Ramírez had a three-run homer in the first inning, Brayan Rocchio delivered a two-run single in the seventh, and the Cleveland Guardians pulled away for a 10-5 victory over the Baltimore Orioles on Monday night.

Jose Ramirez hit a three-run homer and Bo Naylor and Kyle Manzardo had solo shots as the Cleveland Guardians beat the visiting Baltimore Orioles 10-5 in their series opener Monday night.

The Guardians (49-50) have won nine of their last 11 games since ending their 10-game losing streak. They trail first-place Detroit by 10 games and are 3 1/2 games behind the Red Sox for the third wild card spot. Tampa Bay (52-49) and Texas (51-50) are in front of them.