Israeli airstrikes hit Tehran, causing casualties and prompting residents to flee. A human rights group reports hundreds dead in Iran. Tensions escalate as Iran and the US trade threats. Donald Trump demands Iran's surrender.

Iran has not been publishing regular death tolls during the conflict, its last update, issued Monday, put the death toll at 224 people killed and 1,277 others wounded. Iran has retaliated against Israel’s airstrike campaign by launching some 400 missiles and hundreds of drones at Israel.

For nearly six nights, sirens have blared across Israel warning of retaliatory Iranian strikes. While Israel is able to inflict far greater pain on Iran, it has not been immune to destruction and death.