Because of its alpha-cell nature and the presence of clinical diabetes, portions of the tumor were assayed for glucagon by the specific radioactive immunoassay previously described by Unger et al ...

MIT researchers have developed an implant that releases glucagol under the control of external sensors to protect diabetes ...

Most treatments for diabetes focus on insulin, but its counterpart -- the hormone glucagon that is produced by alpha cells in the pancreas -- has received comparatively little attention, says ...

Beta cells play a key role in the pathogenesis of both Type 1 and Type 2 diabetes. However, pancreatic islets also have alpha cells that produce the hormone glucagon, which acts to raise glucose blood ...

Other cells in the pancreas, called alpha cells, produce glucagon, which increases the amount of glucose that the liver releases into the bloodstream. In type 1 diabetes, the immune system targets ...

Most treatments for diabetes focus on insulin, but its counterpart - the hormone glucagon that is produced by alpha cells in the pancreas - has received comparatively little attention, says study ...

Aberrant glucagon responses promoting hyperglycemia may be due to the impaired regulation of glucagon and insulin secretion, as well as disrupted alpha cell responses to insulin. 1,2 ...

“We found ILC2s within the islets of Langerhans and ILC2s or ILC2-derived cytokines triggered pancreatic alpha cells to secrete glucagon in vitro,” the authors explained.

Following beta cell loss in mice, 1-2% of glucagon-producing α-cells spontaneously engage in insulin production. In this study, this was increased to 5%, providing new insights on cell flexibility and ...

In 2010, Herrera and his researchers discovered that if beta cells die prematurely, the pancreatic cells responsible for producing other hormones such as glucagon, which counteracts insulin’s ...

In groundbreaking diabetes research over the past two decades, Anath Shalev, M.D., has shown that the protein TXNIP regulates survival and function of beta cells, the pancreatic cells that produce the ...

Blocking cell receptors for glucagon, the counter-hormone to insulin, cured mouse models of diabetes by converting glucagon-producing cells into insulin producers instead, a team led by UT ...