In mouse models of type 1 diabetes, the secretion of glucagon for the counter-regulation of blood sugar levels is restored ...

The research sheds new light on how this enzyme influences glucagon secretion in pancreatic alpha (α) cells, a process crucial for maintaining healthy blood sugar levels. The research ...

Glucagon-like peptide-1 (GLP-1 ... It is secreted by enteroendocrine cells in response to nutrient intake, and its secretion is influenced by various mechanisms involving different nutrients.

[1] In the presence of elevated glucose concentrations, GLP-1 and GIP increase insulin release and GLP-1 lowers glucagon secretion, thereby modulating the postmeal rise in glucose concentration ...

Boosting Bacteroides vulgatus in diabetic mice increased GLP-1 secretion, improving blood sugar control and reducing sugar ...

“Fasting or high energy–consumption sports activities can result in low plasma glucose concentrations and in response, glucagon secretion is stimulated to promote endogenous glucose production ...

A study on GLP1RA medications found that behavioral side effects likely do not result from direct action on GLP1R.

Explore how GLP-1 agonists, originally for diabetes, could transform addiction treatment by reducing cravings.

In addition to impaired insulin secretion, type 2 diabetic patients also have elevated levels of glucagon, which worsens hyperglycemia by increasing glucose production by the liver. Type 2 ...

Several DPP-4 inhibitors are in clinical development; these are orally active and increase levels of active GLP-1, which in turn increases insulin secretion and reduces glucagon secretion and ...

Additionally, it also decreases glucagon secretion and slows gastric emptying. <10yrs: not established. Give by SC inj in abdomen, thigh, or upper arm; rotate inj sites. Inject immediately after ...