Following a shocking flurry of roster moves, the Giants erased a five-run deficit against the San Diego Padres to beat their divisional rival, 6-5, snapping a streak of 16 consecutive games without scoring more than four runs.

The San Francisco Giants snapped a seven-game losing streak against the San Diego Padres with a comeback win on Wednesday night.

Ray matched his season-best strikeout total, passed Paul Skenes on the National League leaderboard and powered the Giants to a split in their four-game series with the Padres on Thursday. In his first start since being named the National League’s pitcher of the month, Ray struck out nine over seven innings in a 3-2 win.

Pregame analysis and predictions of the San Diego Padres vs. San Francisco Giants MLB game to be played on June 5, 2025 on ESPN.

Get San Francisco vs San Diego baseball betting preview, spread and over/under insights for their matchup on June 4.

The San Diego Padres face the San Francisco Giants Wednesday in the third game of a 4-game set at Oracle Park.

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The struggling San Francisco Giants designated infielder-outfielder LaMonte Wade Jr. for assignment along with catcher Sam Huff

The San Francisco Giants designated popular first baseman LaMonte Wade for assignment on Wednesday after he struggled immensely to start the 2025 season, hitting just .167 with a single home run.

The San Francisco Giants designated veteran first baseman LaMonte Wade Jr. for assignment on Wednesday and signed former first-round pick Dominic Smith to a major league contract, among several moves.