The Ohio-based biotech entrepreneur has emerged as a leading contender to succeed Vice President-elect JD Vance in the U.S. Senate.

Gov. Mike DeWine must pick someone to replace Vice President-elect JD Vance, who resigned his Senate seat last week.

Ramaswamy’s remarks on the H-1B program drew from his personal experience. The son of Indian immigrants who came to the U.S. on work visas, he excelled academically, becoming valedictorian at St. Xavier High School in Cincinnati. His upbringing informed his critique of American culture, which he believes undervalues hard work and innovation.

Ramaswamy fell off the grid in the wake of a contentious and public debate between incoming Trump administration figures over the H-1B visa program.

Ohio Gov. Mike DeWine’s frontrunner for the vacancy is Lt. Gov. Jon Husted — not Ramaswamy, Republican operatives told The Post.

President-elect Donald Trump has privately encouraged Vivek Ramaswamy to consider an appointment to the US Senate seat recently vacated by Vice President-elect JD Vance if offered the position by Ohio Gov.

Neither Lara Trump nor Vivek Ramaswamy will join the Senate. But it’s likely the president-elect didn’t really go to the mat for their appointments.

The co-leader of the “Department of Government Efficiency” could move to replace JD Vance in the Senate, though other contenders remain.

Vivek Ramaswamy is a top contender for Ohio's vacant Senate seat, supported by Donald Trump and Elon Musk. Although he withdrew his candidacy in Novem

Appointing Ramaswamy to the Senate would offer Ohio Lt. Gov. Jon Husted a cleaner shot to succeed DeWine by eliminating a potential competitor.“DeWine isn’t incentivized to pick Ramaswamy for Senate, but Vivek is also the one roadblock to Husted,” this person said.

Recent speculations are on the rise that Vivek Ramaswamy might take the Ohio seat which is being eventually vacated by US Vice President- elect JD Vance. Latest reports are claiming that US President- elect Donald Trump have personally urged Vivek Ramaswamy to do so.