Ekberg and colleagues proposed that in type 1 diabetes a deficiency of C peptide, a subunit of the proinsulin molecule, also contributes to nerve damage; their animal studies showed that C-peptide ...

Four weeks post-transplant, UP421 showed survival and insulin production, verified by C-peptide levels and MRI imaging. No safety issues were reported, and HIP-modified islet cells evaded immune ...

The assessment of fetal and maternal B-cell function by C-peptide measurement requires an understanding of its metabolism in pregnancy. We gave 125 I-tyrosylated-C-peptide (I-CP) to 6 pregnant ...