Since the delayed hyperglycemic effect of zinc glucagon observed in Case 2 (curve "a", Fig. 3) might be due to plasma-binding proteins for glucagon Dr. Jesse Roth, of the National Institutes of ...

Some people, such as those with diabetes, are unable to produce or use insulin or glucagon effectively. In this case, healthcare providers prescribe insulin and glucagon as medications that people ...

Glucagon acts primarily at the level of the liver to increase glucose production by liver cells, either by the breakdown of glycogen to glucose or by de novo synthesis of glucose.

“Collectively, these results suggest that inhibiting glucagon receptor action can promote recovery of functional β-cell mass in murine models of type 1 diabetes,” the team commented.

WebMD explains how the hormone glucagon helps balance your blood sugar and treat hypoglycemia.

Glucagon prescriptions for severe hypoglycemia rose in Medicaid beneficiaries with the introduction of newer products but likely met only a fraction of the high-risk population’s needs.

Small-molecule antagonists of glucagon receptor (GCGR), a class B G protein-coupled receptor, reduce plasma glucose levels in patients with type 2 diabetes. Jazayeri et al. now report the 2.5 Å ...

Although it is also involved in binding to glucagon, this "transmembrane domain" of the receptor -- which resembles a jumble of 7 loose springs -- tends to resist the crystallization that is ...

While wholesale costs for glucagon skyrocketed over the past decade, out-of-pocket costs haven't increased by much, researchers reported. The cost of unmixed glucagon increased 192% from 2010 to ...

Binding of a specific ligand to the glucagon receptor triggers the release of glucose from the liver during fasting, making this receptor a critical component for maintaining normal glucose levels ...

G protein-coupled receptors (GPCRs) play essential roles in cell signal transduction and serve as important therapeutic targets for a large number of diseases. Upon binding to extracellular ...