DPP-4 has a higher selectivity for glucagon-like peptide (GLP)-1, GLP-2, neuropeptide Y and peptide YY, than DPP-8 and -9. [7] Both GLP-1 and glucose-dependent insulinotropic peptide (GIP) are ...

Oxyntomodulin and peptide tyrosine-tyrosine (PYY) are released from intestinal enteroendocrine cells in response to a meal. These circulating hormones are considered to be satiety signals, as they ...

Transferrin receptor 1 (TfR1) is a ubiquitously expressed receptor characterized by rapid internalization kinetics and efficient receptor recycling, making it an attractive target for drug delivery.

The L-cell, another EEC subtype, is known for its role in secreting hormones, such as peptide YY (PYY) and glucagon-like peptide-1 (GLP-1), and sensing postprandial nutrients. Exogenous administration ...

UpdatedMarch 7, 2025, 1:28 PM EST Deanna Pai Contributing Writer and Editor Mili Godio Updates Editor + 1 more ...

If you’ve ever skimmed the label of a fancy serum or moisturiser, chances are you’ve seen the word peptides printed in bold. But what exactly are they—and are they worth the buzz (and bucks)? Spoiler: ...

Bottom-up fabrication of self-assembled nanomaterials requires control over forces and interactions between building blocks. We report here on the formation and architecture of supramolecular ...

GIP looks a lot like GLP-1, so rather than administer two drugs, researchers created one peptide that incorporates structural elements of both—what’s called in drug development a chimera.