Ryan Reynolds/YouTube; ABC Photo Archives/Disney General Entertainment Content via Getty Ryan Reynolds in 'Doogie Howser M.D.' spoof; Neil Patrick Harris in a 1989 photo from the real thing More ...

And since Neil Patrick Harris is filling that role in the newly announced Marvel’s Deadpool VR, Reynolds responded exactly how you’d imagine: by taking over as Doogie Howser.

Step aside, Ryan Reynolds, because famed sitcom star Neil Patrick Harris will officially portray Marvel's infamous Merc with a Mouth in an upcoming VR game.

From a kid doctor to a sitcom playboy, the best Neil Patrick Harris movies and TV shows reflect both the actor's comedic and dramatic talents.

Neil Patrick Harris: I read the script with one hand covering my eye and shook my head at the depiction of who these writers thought I was.

A VR game based on Marvel's "Deadpool" franchise is set to launch later this year from Meta Quest with Neil Patrick Harris starring.

Just weeks after Grand Prix weekend brought a parade of stars like Ben Stiller and Mumford and Sons to the city, even more big names are set to roll through Montreal this July. Whether you're heading ...

Five-time Emmy winner Neil Patrick Harris (“A Series of Unfortunate Events”, “Gone Girl”), BAFTA nominee James Norton (“Joy”, “Bob Marley: One Love”), and recent Golden Globe and ...

Ryan Reynolds spoofs “Doogie Howser M.D.”, calls Neil Patrick Harris a 'butthole' for stealing Deadpool game role Harris is set to voice the merc with a mouth in 'Marvel’s Deadpool VR' for ...

Developed by Twisted Pixel and Oculus Studios, in collaboration with Marvel Games, “Marvel’s Deadpool VR” features a new story focused around the MCU character portrayed by Ryan Reynolds in ...