RB Isaac Guerendo was dealing with a hamstring injury. Here are the latest updates leading up to Week 17’s game vs. the Lions ...

Way back in Week 4, 49ers rookie guard Dominick Puni had the wind knocked out of him and had to miss a snap. He hasn’t been ...

Nolan Bianchi, John Niyo, Richard Silva and Bob Wojnowski of The Detroit News offer predictions for Monday's Lions-49ers game ...

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San Francisco 49ers running back Isaac Guerendo is expected to play Monday night against the Detroit Lions, according to ESPN ...

Who are the 10 greatest San Francisco 49ers of all time? FOX Sports Research compiled the list of Niner greats.

Coach Dan Campbell stood at the podium after Detroit blew a 17-point lead to San Francisco in last season's NFC title game ...

MIAMI -- This is the live blog for the San Francisco 49ers' Week 16 road game against the Miami Dolphins. This will be ...

NFL Week 17 odds, picks, predictions, TV channel, streaming information for Monday Night Football game between Detroit Lions ...

Kader Kohou left his feet for a game-sealing interception, helping the Miami Dolphins preserve a late lead over the San ...

Tua Tagovailoa threw the 100th passing touchdown of his career, and the Miami Dolphins defeated the San Francisco 49ers on ...

Tua Tagovailoa threw for 215 yards and a touchdown, Jason Sanders nailed five field goals, and the Miami Dolphins kept their ...