Because of its alpha-cell nature and the presence of clinical diabetes, portions of the tumor were assayed for glucagon by the specific radioactive immunoassay previously described by Unger et al ...

MIT researchers have developed an implant that releases glucagol under the control of external sensors to protect diabetes ...

Blocking cell receptors for glucagon, the counter-hormone to insulin, cured mouse models of diabetes by converting glucagon-producing cells into insulin producers instead, a team reports in a new ...

Other cells in the pancreas, called alpha cells, produce glucagon, which increases the amount of glucose that the liver releases into the bloodstream.

However, glucagon secretion was decreased more than twofold in the aTKO islets compared to controls. Out of five proteins recently reported to be involved in alpha cell glucagon expression, only one, ...

Antibodies that convert glucagon-producing cells into insulin-producing ones cure mouse models of the diabetes.

Glucagon is a peptide hormone secreted primarily from the alpha cells of the pancreatic islets of Langerhans. Minor amounts are also produced in the L cells of the intestine and certain neurons of ...

This work was recently published in Stem Cell Reports. These stem cell-derived alpha cells very closely resembled pancreas-derived alpha cells and secreted comparable levels of glucagon.

Glucagon is secreted to the blood by alpha cells located in the pancreatic islet of Langerhans, the authors explained.

The beta cells of the pancreas don’t need the assistance of other pancreatic cells to produce insulin, according to new research. The findings are not only a potential game-changer for diabetics ...

Beta cells play a key role in the pathogenesis of both Type 1 and Type 2 diabetes. However, pancreatic islets also have alpha cells that produce the hormone glucagon, which acts to raise glucose blood ...