Proglucagon-derived peptides (PGDPs), including glucagon, GLP-1, and GLP-2, are known to be the key hormones that regulate ...

Proglucagon-derived peptides from the pancreas and gut regulate various aspects of energy homeostasis, with many potential therapeutic applications—glucagon is used to treat hypoglycemia, and ...

Proglucagon-derived peptides are involved in a wide variety of both peripheral as well as central functions, such as glucose homeostasis, gastric emptying, insulin secretion and the regulation of ...

Proglucagon-derived peptides (PGDPs), including glucagon, GLP-1, and GLP-2, are known to regulate lipid metabolism in the liver. However, the mechanism underlying this remains unelucidated.

Proglucagon-derived peptides (PGDPs), including glucagon, GLP-1, and GLP-2, are known to be the key hormones that regulate lipid metabolism in the liver. Derived from the same precursor ...

GCG: Directs the production of Proglucagon, a precursor protein essential for GLP-1 synthesis. PCSK1: Encodes for enzymes that cleave Proglucagon into active GLP-1.

1) What impact do proglucagon and GIP gene peptide products have on pancreatic beta-cell function? We will assess secretory and functional effects of all peptide products on pancreatic alpha- and beta ...

In the intestine and brain, PC1 converts proglucagon to the incretin hormones, glucagon-like peptide 1 (GLP-1) and glucagon-like peptide 2 (GLP-2). 1,2 . Image Credit: DiBtv/Shutterstock.com.

GLP-1, or glucagon-like peptide 1, is a hormone comprising 30 amino acids considered to be created in the intestinal epithelium’s endocrine L cells. These L cells make GLP-1 by the differential ...

Proglucagon-derived peptides (PGDPs), including glucagon, GLP-1, and GLP-2, are known to be the key hormones that regulate lipid metabolism in the liver.