Ryan Reynolds/YouTube; ABC Photo Archives/Disney General Entertainment Content via Getty Ryan Reynolds in 'Doogie Howser M.D.' spoof; Neil Patrick Harris in a 1989 photo from the real thing More ...

And since Neil Patrick Harris is filling that role in the newly announced Marvel’s Deadpool VR, Reynolds responded exactly how you’d imagine: by taking over as Doogie Howser.

Step aside, Ryan Reynolds, because famed sitcom star Neil Patrick Harris will officially portray Marvel's infamous Merc with a Mouth in an upcoming VR game.

A VR game based on Marvel's "Deadpool" franchise is set to launch later this year from Meta Quest with Neil Patrick Harris starring.

Marvel has announced a new VR game centred around Deadpool, from the studio behind 'Splosion Man and Comic Jumper.

Ryan Reynolds spoofs “Doogie Howser M.D.”, calls Neil Patrick Harris a 'butthole' for stealing Deadpool game role Harris is set to voice the merc with a mouth in 'Marvel’s Deadpool VR' for ...

A VR game based on Marvel’s “Deadpool” franchise is set to launch later this year from Meta Quest with Neil Patrick Harris voicing the Merc with a Mouth. Developed by Twisted Pixel and ...

Marvel's Deadpool VR is a new action game coming later this year, featuring the voice of Neil Patrick Harris instead of Ryan Reynolds.